In situ architecture of the lipid transport protein VPS13C at ER–lysosome membrane contacts

VPS13 is a eukaryotic lipid transport protein localized at membrane contact sites. Previous studies suggested that it may transfer lipids between adjacent bilayers by a bridge-like mechanism. Direct evidence for this hypothesis from a full-length structure and from electron microscopy (EM) studies i...

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Detalles Bibliográficos
Autores principales: Cai, Shujun, Wu, Yumei, Guillén-Samander, Andrés, Hancock-Cerutti, William, Liu, Jun, De Camilli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303930/
https://www.ncbi.nlm.nih.gov/pubmed/35858323
http://dx.doi.org/10.1073/pnas.2203769119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303930/
https://www.ncbi.nlm.nih.gov/pubmed/35858323
http://dx.doi.org/10.1073/pnas.2203769119

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