Dosing Regimen Prediction and Confirmation With Rivaroxaban for Thromboprophylaxis in Children After the Fontan Procedure: Insights From the Phase III UNIVERSE Study

Thrombosis remains an important complication for children with single‐ventricle physiology following the Fontan procedure, and effective thromboprophylaxis is an important unmet medical need. To obviate conventional dose‐finding studies and expedite clinical development, a rivaroxaban dose regimen f...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Peijuan, Willmann, Stefan, Zhou, Wangda, Yang, Haitao, Michelson, Alan D., McCrindle, Brian W., Li, Jennifer S., Harris, Kevin C., Pina, Liza Miriam, Weber, Traci, Nessel, Kimberly, Lesko, Lawrence J., Kubitza, Dagmar, Zannikos, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Editor's Choice: Pediatric Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303933/
https://www.ncbi.nlm.nih.gov/pubmed/34524700
http://dx.doi.org/10.1002/jcph.1966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303933/
https://www.ncbi.nlm.nih.gov/pubmed/34524700
http://dx.doi.org/10.1002/jcph.1966

Ejemplares similares