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Pathogenic Tconvs promote inflammatory macrophage polarization through GM‐CSF and exacerbate abdominal aortic aneurysm formation

Abdominal aortic aneurysms (AAAs) elicit massive inflammatory leukocyte recruitment to the aorta. CD4(+) T cells, which include regulatory T cells (Tregs) and conventional T cells (Tconvs), are involved in the progression of AAA. Tregs have been reported to limit AAA formation. However, the function...

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Detalles Bibliográficos
Autores principales: Li, Dan, Li, Jingyong, Liu, Henan, Zhai, Luna, Hu, Wangling, Xia, Ni, Tang, Tingting, Jiao, Jiao, Lv, Bingjie, Nie, Shaofang, Hu, Desheng, Liao, Yuhua, Yang, Xiangping, Shi, Guo‐Ping, Cheng, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303938/
https://www.ncbi.nlm.nih.gov/pubmed/35133017
http://dx.doi.org/10.1096/fj.202101576R