Cargando…
Pathogenic Tconvs promote inflammatory macrophage polarization through GM‐CSF and exacerbate abdominal aortic aneurysm formation
Abdominal aortic aneurysms (AAAs) elicit massive inflammatory leukocyte recruitment to the aorta. CD4(+) T cells, which include regulatory T cells (Tregs) and conventional T cells (Tconvs), are involved in the progression of AAA. Tregs have been reported to limit AAA formation. However, the function...
Autores principales: | Li, Dan, Li, Jingyong, Liu, Henan, Zhai, Luna, Hu, Wangling, Xia, Ni, Tang, Tingting, Jiao, Jiao, Lv, Bingjie, Nie, Shaofang, Hu, Desheng, Liao, Yuhua, Yang, Xiangping, Shi, Guo‐Ping, Cheng, Xiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303938/ https://www.ncbi.nlm.nih.gov/pubmed/35133017 http://dx.doi.org/10.1096/fj.202101576R |
Ejemplares similares
-
Aorta Regulatory T Cells with a Tissue‐Specific Phenotype and Function Promote Tissue Repair through Tff1 in Abdominal Aortic Aneurysms
por: Li, Jingyong, et al.
Publicado: (2022) -
Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation
por: Yang, Fen, et al.
Publicado: (2022) -
Cholesterol suppresses human iTreg differentiation and nTreg function through mitochondria-related mechanisms
por: Zhang, Huanzhi, et al.
Publicado: (2023) -
Regulatory T cells and cardiovascular diseases
por: Hu, Wangling, et al.
Publicado: (2023) -
GM-CSF in inflammation
por: Hamilton, John A.
Publicado: (2019)