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Biosynthesis of 3-thia-α-amino acids on a carrier peptide

A subset of natural products, such as polyketides and nonribosomal peptides, is biosynthesized while tethered to a carrier peptide via a thioester linkage. Recently, we reported that the biosyntheses of 3-thiaglutamate and ammosamide, single amino acid–derived natural products, employ a very differe...

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Detalles Bibliográficos
Autores principales: Yu, Yue, van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303977/
https://www.ncbi.nlm.nih.gov/pubmed/35787182
http://dx.doi.org/10.1073/pnas.2205285119