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Biosynthesis of 3-thia-α-amino acids on a carrier peptide
A subset of natural products, such as polyketides and nonribosomal peptides, is biosynthesized while tethered to a carrier peptide via a thioester linkage. Recently, we reported that the biosyntheses of 3-thiaglutamate and ammosamide, single amino acid–derived natural products, employ a very differe...
Autores principales: | Yu, Yue, van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303977/ https://www.ncbi.nlm.nih.gov/pubmed/35787182 http://dx.doi.org/10.1073/pnas.2205285119 |
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