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A novel transposable element-mediated mechanism causes antiviral resistance in Drosophila through truncating the Veneno protein

Hosts are continually selected to evolve new defenses against an ever-changing array of pathogens. To understand this process, we examined the genetic basis of resistance to the Drosophila A virus in Drosophila melanogaster. In a natural population, we identified a polymorphic transposable element (...

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Detalles Bibliográficos
Autores principales: Brosh, Osama, Fabian, Daniel K., Cogni, Rodrigo, Tolosana, Ignacio, Day, Jonathan P., Olivieri, Francesca, Merckx, Manon, Akilli, Nazli, Szkuta, Piotr, Jiggins, Francis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304006/
https://www.ncbi.nlm.nih.gov/pubmed/35858337
http://dx.doi.org/10.1073/pnas.2122026119