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DNA damage reduces heterogeneity and coherence of chromatin motions

Chromatin motions depend on and may regulate genome functions, in particular the DNA damage response. In yeast, DNA double-strand breaks (DSBs) globally increase chromatin diffusion, whereas in higher eukaryotes the impact of DSBs on chromatin dynamics is more nuanced. We mapped the motions of chrom...

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Detalles Bibliográficos
Autores principales: Locatelli, Maëlle, Lawrimore, Josh, Lin, Hua, Sanaullah, Sarvath, Seitz, Clayton, Segall, Dave, Kefer, Paul, Salvador Moreno, Naike, Lietz, Benton, Anderson, Rebecca, Holmes, Julia, Yuan, Chongli, Holzwarth, George, Bloom, Kerry S., Liu, Jing, Bonin, Keith, Vidi, Pierre-Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304018/
https://www.ncbi.nlm.nih.gov/pubmed/35858349
http://dx.doi.org/10.1073/pnas.2205166119