Insulin regulates neurovascular coupling through astrocytes

Mice with insulin receptor (IR)–deficient astrocytes (GFAP-IR knockout [KO] mice) show blunted responses to insulin and reduced brain glucose uptake, whereas IR-deficient astrocytes show disturbed mitochondrial responses to glucose. While exploring the functional impact of disturbed mitochondrial fu...

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Detalles Bibliográficos
Autores principales: Fernandez, Ana M., Martinez-Rachadell, Laura, Navarrete, Marta, Pose-Utrilla, Julia, Davila, Jose Carlos, Pignatelli, Jaime, Diaz-Pacheco, Sonia, Guerra-Cantera, Santiago, Viedma-Moreno, Emilia, Palenzuela, Rocio, Ruiz de Martin Esteban, Samuel, Mostany, Ricardo, Garcia-Caceres, Cristina, Tschöp, Matthias, Iglesias, Teresa, de Ceballos, Maria L., Gutierrez, Antonia, Torres Aleman, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304019/
https://www.ncbi.nlm.nih.gov/pubmed/35858325
http://dx.doi.org/10.1073/pnas.2204527119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304019/
https://www.ncbi.nlm.nih.gov/pubmed/35858325
http://dx.doi.org/10.1073/pnas.2204527119

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