Epithelial chemerin–CMKLR1 signaling restricts microbiota-driven colonic neutrophilia and tumorigenesis by up-regulating lactoperoxidase

Intestinal barrier immunity is essential for controlling gut microbiota without eliciting harmful immune responses, while its defect contributes to the breakdown of intestinal homeostasis and colitis development. Chemerin, which is abundantly expressed in barrier tissues, has been demonstrated to re...

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Detalles Bibliográficos
Autores principales: Lin, Yuli, Cai, Qian, Luo, Yaxin, Li, Bingji, Chen, Yu, Yang, Xuguang, Xuan, Yan, Yang, Huifan, He, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304024/
https://www.ncbi.nlm.nih.gov/pubmed/35858331
http://dx.doi.org/10.1073/pnas.2205574119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304024/
https://www.ncbi.nlm.nih.gov/pubmed/35858331
http://dx.doi.org/10.1073/pnas.2205574119

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