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Therapeutic functions of astrocytes to treat α-synuclein pathology in Parkinson’s disease

Intraneuronal inclusions of misfolded α-synuclein (α-syn) and prion-like spread of the pathologic α-syn contribute to progressive neuronal death in Parkinson’s disease (PD). Despite the pathologic significance, no efficient therapeutic intervention targeting α-synucleinopathy has been developed. In...

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Detalles Bibliográficos
Autores principales: Yang, Yunseon, Song, Jae-Jin, Choi, Yu Ree, Kim, Seong-hoon, Seok, Min-Jong, Wulansari, Noviana, Darsono, Wahyu Handoko Wibowo, Kwon, Oh-Chan, Chang, Mi-Yoon, Park, Sang Myun, Lee, Sang-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304026/
https://www.ncbi.nlm.nih.gov/pubmed/35858361
http://dx.doi.org/10.1073/pnas.2110746119