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Sequential rescue and repair of stalled and damaged ribosome by bacterial PrfH and RtcB

RtcB is involved in transfer RNA (tRNA) splicing in archaeal and eukaryotic organisms. However, most RtcBs are found in bacteria, whose tRNAs have no introns. Because tRNAs are the substrates of archaeal and eukaryotic RtcB, it is assumed that bacterial RtcBs are for repair of damaged tRNAs. Here, w...

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Detalles Bibliográficos
Autores principales: Tian, Yannan, Zeng, Fuxing, Raybarman, Adrika, Fatma, Shirin, Carruthers, Amy, Li, Qingrong, Huang, Raven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304027/
https://www.ncbi.nlm.nih.gov/pubmed/35858322
http://dx.doi.org/10.1073/pnas.2202464119