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Enhanced incorporation of subnanometer tags into cellular proteins for fluorescence nanoscopy via optimized genetic code expansion

With few-nanometer resolution recently achieved by a new generation of fluorescence nanoscopes (MINFLUX and MINSTED), the size of the tags used to label proteins will increasingly limit the ability to dissect nanoscopic biological structures. Bioorthogonal (click) chemical groups are powerful tools...

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Detalles Bibliográficos
Autores principales: Mihaila, Tiberiu S., Bäte, Carina, Ostersehlt, Lynn M., Pape, Jasmin K., Keller-Findeisen, Jan, Sahl, Steffen J., Hell, Stefan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304028/
https://www.ncbi.nlm.nih.gov/pubmed/35858298
http://dx.doi.org/10.1073/pnas.2201861119