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A broad and potent neutralization epitope in SARS-related coronaviruses

Many neutralizing antibodies (nAbs) elicited to ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through natural infection and vaccination have reduced effectiveness to SARS-CoV-2 variants. Here, we show that therapeutic antibody ADG20 is able to neutralize SARS-CoV-2 variants...

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Detalles Bibliográficos
Autores principales: Yuan, Meng, Zhu, Xueyong, He, Wan-ting, Zhou, Panpan, Kaku, Chengzi I., Capozzola, Tazio, Zhu, Connie Y., Yu, Xinye, Liu, Hejun, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Peng, Linghang, Song, Ge, Cottrell, Christopher A., Schief, William R., Nemazee, David, Walker, Laura M., Andrabi, Raiees, Burton, Dennis R., Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304036/
https://www.ncbi.nlm.nih.gov/pubmed/35767670
http://dx.doi.org/10.1073/pnas.2205784119