CHARGE syndrome‐associated proteins FAM172A and CHD7 influence male sex determination and differentiation through transcriptional and alternative splicing mechanisms

To gain further insight into chromatin‐mediated regulation of mammalian sex determination, we analyzed the role of the CHARGE syndrome‐associated proteins FAM172A and CHD7. This study is based on our prior discoveries that a subset of corresponding mutant mice display complete male‐to‐female sex rev...

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Detalles Bibliográficos
Autores principales: Bélanger, Catherine, Cardinal, Tatiana, Leduc, Elizabeth, Viger, Robert S., Pilon, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304217/
https://www.ncbi.nlm.nih.gov/pubmed/35129866
http://dx.doi.org/10.1096/fj.202100837RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304217/
https://www.ncbi.nlm.nih.gov/pubmed/35129866
http://dx.doi.org/10.1096/fj.202100837RR

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