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DDX17‐regulated alternative splicing that produced an oncogenic isoform of PXN‐AS1 to promote HCC metastasis

BACKGROUND AND AIMS: The mechanism underlying HCC metastasis remains unclear, many oncogenes are known to regulate this process. However, the role of alternative splicing (AS) in pro‐metastatic HCC is poorly understood. APPROACH AND RESULTS: By performing RNA sequencing on nine pairs of primary HCC...

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Detalles Bibliográficos
Autores principales: Zhou, Hong‐Zhong, Li, Fan, Cheng, Sheng‐Tao, Xu, Yong, Deng, Hai‐Jun, Gu, Da‐Yong, Wang, Jin, Chen, Wei‐Xian, Zhou, Yu‐Jiao, Yang, Min‐Li, Ren, Ji‐Hua, Zheng, Lu, Huang, Ai‐Long, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304246/
https://www.ncbi.nlm.nih.gov/pubmed/34626132
http://dx.doi.org/10.1002/hep.32195