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A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 4: Core Fragments with Two Halide Leaving Groups Featuring Side Chains of Proteinogenic Amino Acids

Teraryl‐based α‐helix mimetics have proven to be useful compounds for the inhibition of protein‐protein interactions (PPI). We have developed a modular and flexible approach for the synthesis of teraryl‐based α‐helix mimetics using a benzene core unit featuring two halide leaving groups of different...

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Detalles Bibliográficos
Autores principales: Trobe, Melanie, Blesl, Julia, Vareka, Martin, Schreiner, Till, Breinbauer, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304293/
https://www.ncbi.nlm.nih.gov/pubmed/35910460
http://dx.doi.org/10.1002/ejoc.202101279