Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor

Type 1 diabetes (T1D) is an autoimmune disease that selectively destroys insulin-producing β-cells in the pancreas. An unmet need in diabetes management, current therapy is focussed on transplantation. While the reprogramming of progenitor cells into functional insulin-producing β-cells has also bee...

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Detalles Bibliográficos
Autores principales: Al-Hasani, Keith, Khurana, Ishant, Mariana, Lina, Loudovaris, Thomas, Maxwell, Scott, Harikrishnan, K. N., Okabe, Jun, Cooper, Mark E., El-Osta, Assam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304326/
https://www.ncbi.nlm.nih.gov/pubmed/35864094
http://dx.doi.org/10.1038/s41392-022-01034-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304326/
https://www.ncbi.nlm.nih.gov/pubmed/35864094
http://dx.doi.org/10.1038/s41392-022-01034-7

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