FUNDC1-mediated mitophagy and HIF1α activation drives pulmonary hypertension during hypoxia

Hypoxic pulmonary hypertension (PH) is a progressive disease characterized by hyper-proliferation of pulmonary vascular cells including pulmonary artery smooth muscle cells (PASMCs) and can lead to right heart failure and early death. Selective degradation of mitochondria by mitophagy during hypoxia...

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Detalles Bibliográficos
Autores principales: Liu, Ruxia, Xu, Chunling, Zhang, Weilin, Cao, Yangpo, Ye, Jingjing, Li, Bo, Jia, Shi, Weng, Lin, Liu, Yingying, Liu, Lei, Zheng, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304375/
https://www.ncbi.nlm.nih.gov/pubmed/35864106
http://dx.doi.org/10.1038/s41419-022-05091-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304375/
https://www.ncbi.nlm.nih.gov/pubmed/35864106
http://dx.doi.org/10.1038/s41419-022-05091-2

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