Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells

Monoclonal antibodies (abs) targeting the programmed cell death 1 (PD-1) immune checkpoint pathway have revolutionized tumor therapy. Because T-cell-directed PD-1 blockade boosts tumor immunity, anti-PD-1 abs have been developed for examining T-cell-PD-1 functions. More recently, PD-1 expression has...

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Detalles Bibliográficos
Autores principales: Martins, Christina, Silva, Mariana, Rasbach, Erik, Singh, Praveen, Itoh, Yuta, Williams, Jason B., Statham, Edith, Meurer, Anna, Martinez, Daniela V., Brandenburg, Anne, Heppt, Markus V., Barthel, Steven R., Schatton, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304406/
https://www.ncbi.nlm.nih.gov/pubmed/35864188
http://dx.doi.org/10.1038/s41598-022-16776-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304406/
https://www.ncbi.nlm.nih.gov/pubmed/35864188
http://dx.doi.org/10.1038/s41598-022-16776-1

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