In silico performance analysis of web tools for CRISPRa sgRNA design in human genes

Angiogenic gene overexpression has been the main strategy in numerous vascular regenerative gene therapy projects. However, most have failed in clinical trials. CRISPRa technology enhances gene overexpression levels based on the identification of sgRNAs with maximum efficiency and safety. CRISPick a...

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Detalles Bibliográficos
Autores principales: Nuñez Pedrozo, Cristian N., Peralta, Tomás M., Olea, Fernanda D., Locatelli, Paola, Crottogini, Alberto J., Belaich, Mariano N., Cuniberti, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304428/
https://www.ncbi.nlm.nih.gov/pubmed/35891794
http://dx.doi.org/10.1016/j.csbj.2022.07.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304428/
https://www.ncbi.nlm.nih.gov/pubmed/35891794
http://dx.doi.org/10.1016/j.csbj.2022.07.023

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