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Comparison of Methods Utilizing Sex-Specific PRSs Derived From GWAS Summary Statistics
The polygenic risk score (PRS) is calculated as the weighted sum of an individual’s genotypes and their estimated effect sizes, which is often used to estimate an individual’s genetic susceptibility to complex traits and disorders. It is well known that some complex human traits or disorders have se...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304553/ https://www.ncbi.nlm.nih.gov/pubmed/35873490 http://dx.doi.org/10.3389/fgene.2022.892950 |