Elimination of Senescent Cells by Senolytics Facilitates Bony Endplate Microvessel Formation and Mitigates Disc Degeneration in Aged Mice

Senolytics are a class of drugs that selectively eliminate senescent cells and ameliorate senescence-associated disease. Studies have demonstrated the accumulation of senescent disc cells and the production of senescence-associated secretory phenotype decrease the number of functional cells in degen...

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Detalles Bibliográficos
Autores principales: Chen, Bolin, Zhu, Runjiu, Hu, Hao, Zhan, Mingbin, Wang, Tingxuan, Huang, Fangli, Wei, Fuxin, Chai, Yu, Ling, Zemin, Zou, Xuenong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304574/
https://www.ncbi.nlm.nih.gov/pubmed/35874831
http://dx.doi.org/10.3389/fcell.2022.853688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304574/
https://www.ncbi.nlm.nih.gov/pubmed/35874831
http://dx.doi.org/10.3389/fcell.2022.853688

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