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Impaired type I interferon signaling activity implicated in the peripheral blood transcriptome of preclinical Alzheimer's disease

BACKGROUND: Subjective or objective subtle cognitive decline (SCD) is considered the preclinical manifestation of Alzheimer's disease (AD), which is a potentially crucial window for preventing or delaying the progression of the disease. METHODS: To explore the potential mechanism of disease pro...

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Detalles Bibliográficos
Autores principales: Song, Liting, Chen, Jingqi, Lo, Chun-Yi Zac, Guo, Qihao, Feng, Jianfeng, Zhao, Xing-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304603/
https://www.ncbi.nlm.nih.gov/pubmed/35863293
http://dx.doi.org/10.1016/j.ebiom.2022.104175