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Evaluation of Caco-2 and human intestinal epithelial cells as in vitro models of colonic and small intestinal integrity

Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) compared to in vivo conditions. Therefore, we investigated Human Intestinal Epithelial Cells (HIECs) as an a...

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Detalles Bibliográficos
Autores principales: Lopez-Escalera, Silvia, Wellejus, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304606/
https://www.ncbi.nlm.nih.gov/pubmed/35873654
http://dx.doi.org/10.1016/j.bbrep.2022.101314