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Single-nucleus chromatin accessibility and RNA sequencing reveal impaired brain development in prenatally e-cigarette exposed neonatal rats

Although emerging evidence reveals that vaping alters the function of the central nervous system, the effects of maternal vaping on offspring brain development remain elusive. Using a well-established in utero exposure model, we performed single-nucleus ATAC-seq (snATAC-seq) and RNA sequencing (snRN...

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Detalles Bibliográficos
Autores principales: Chen, Zhong, Chen, Wanqiu, Li, Yong, Moos, Malcolm, Xiao, Daliao, Wang, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304611/
https://www.ncbi.nlm.nih.gov/pubmed/35874099
http://dx.doi.org/10.1016/j.isci.2022.104686