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NFIA determines the cis-effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes

Thermogenic brown and beige adipocytes counteract obesity by enhancing energy dissipation via uncoupling protein-1 (Ucp1). However, the effect of genetic variation on these cells, a major source of disease susceptibility, has been less well studied. Here we examined beige adipocytes from obesity-pro...

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Detalles Bibliográficos
Autores principales: Hiraike, Yuta, Tsutsumi, Shuichi, Wada, Takahito, Oguchi, Misato, Saito, Kaede, Nakamura, Masahiro, Ota, Satoshi, Koebis, Michinori, Nakao, Harumi, Aiba, Atsu, Nagano, Gaku, Ohno, Haruya, Oki, Kenji, Yoneda, Masayasu, Kadowaki, Takashi, Aburatani, Hiroyuki, Waki, Hironori, Yamauchi, Toshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304612/
https://www.ncbi.nlm.nih.gov/pubmed/35874098
http://dx.doi.org/10.1016/j.isci.2022.104729