Altered MYO5B Function Underlies Microvillus Inclusion Disease: Opportunities for Intervention at a Cellular Level

Microvillus inclusion disease (MVID) is a congenital diarrheal disorder resulting in life-threatening secretory diarrhea in newborns. Inactivating and nonsense mutations in myosin Vb (MYO5B) have been identified in MVID patients. Work using patient tissues, cell lines, mice, and pigs has led to crit...

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Detalles Bibliográficos
Autores principales: Bowman, Deanna M., Kaji, Izumi, Goldenring, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304615/
https://www.ncbi.nlm.nih.gov/pubmed/35660026
http://dx.doi.org/10.1016/j.jcmgh.2022.04.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304615/
https://www.ncbi.nlm.nih.gov/pubmed/35660026
http://dx.doi.org/10.1016/j.jcmgh.2022.04.015

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