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Ferroptosis in Intrahepatic Cholangiocarcinoma: IDH1(105GGT) Single Nucleotide Polymorphism Is Associated With Its Activation and Better Prognosis
OBJECTIVES: Intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis and often demonstrates an anti-apoptotic landscape, which is a key step to chemotherapy resistance. Isocitrate dehydrogenase 1 or 2 (IDH1-2)-mutated ICCs have been described and associated with better prognosis. Ferroptosis is...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304620/ https://www.ncbi.nlm.nih.gov/pubmed/35872783 http://dx.doi.org/10.3389/fmed.2022.886229 |