Ferroptosis in Intrahepatic Cholangiocarcinoma: IDH1(105GGT) Single Nucleotide Polymorphism Is Associated With Its Activation and Better Prognosis

OBJECTIVES: Intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis and often demonstrates an anti-apoptotic landscape, which is a key step to chemotherapy resistance. Isocitrate dehydrogenase 1 or 2 (IDH1-2)-mutated ICCs have been described and associated with better prognosis. Ferroptosis is...

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Autores principales: Sarcognato, Samantha, Sacchi, Diana, Fabris, Luca, Zanus, Giacomo, Gringeri, Enrico, Niero, Monia, Gallina, Giovanna, Guido, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304620/
https://www.ncbi.nlm.nih.gov/pubmed/35872783
http://dx.doi.org/10.3389/fmed.2022.886229

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