Single-Cell Mononucleotide Microsatellite Analysis Reveals Differential Insertion-Deletion Dynamics in Mouse T Cells

Microsatellite sequences are particularly prone to slippage during DNA replication, forming insertion-deletion loops that, if left unrepaired, result in de novo mutations (expansions or contractions of the repeat array). Mismatch repair (MMR) is a critical DNA repair mechanism that corrects these in...

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Detalles Bibliográficos
Autores principales: Aska, Elli-Mari, Zagidullin, Bulat, Pitkänen, Esa, Kauppi, Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304711/
https://www.ncbi.nlm.nih.gov/pubmed/35873465
http://dx.doi.org/10.3389/fgene.2022.913163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304711/
https://www.ncbi.nlm.nih.gov/pubmed/35873465
http://dx.doi.org/10.3389/fgene.2022.913163

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