Cargando…
Single-Cell Mononucleotide Microsatellite Analysis Reveals Differential Insertion-Deletion Dynamics in Mouse T Cells
Microsatellite sequences are particularly prone to slippage during DNA replication, forming insertion-deletion loops that, if left unrepaired, result in de novo mutations (expansions or contractions of the repeat array). Mismatch repair (MMR) is a critical DNA repair mechanism that corrects these in...
Autores principales: | Aska, Elli-Mari, Zagidullin, Bulat, Pitkänen, Esa, Kauppi, Liisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304711/ https://www.ncbi.nlm.nih.gov/pubmed/35873465 http://dx.doi.org/10.3389/fgene.2022.913163 |
Ejemplares similares
-
Single-Cell Sequencing of Mouse Thymocytes Reveals Mutational Landscape Shaped by Replication Errors, Mismatch Repair, and H3K36me3
por: Aska, Elli-Mari, et al.
Publicado: (2020) -
Predicting stability of DNA bulge at mononucleotide microsatellite
por: Bae, Jin H, et al.
Publicado: (2021) -
Mlh1 heterozygosity and promoter methylation associates with microsatellite instability in mouse sperm
por: Shrestha, Kul S, et al.
Publicado: (2021) -
Quasimonomorphic Mononucleotide Repeats for High-Level Microsatellite Instability Analysis
por: Buhard, Olivier, et al.
Publicado: (2004) -
Insertion/deletion and microsatellite alteration profiles in induced pluripotent stem cells
por: Kamimura, Satoshi, et al.
Publicado: (2021)