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Pedunculopontine Nucleus Dysconnectivity Correlates With Gait Impairment in Parkinson’s Disease: An Exploratory Study

BACKGROUND: Gait impairment is a debilitating and progressive feature of Parkinson’s disease (PD). Increasing evidence suggests that gait control is partly mediated by cholinergic signaling from the pedunculopontine nucleus (PPN). OBJECTIVE: We investigated whether PPN structural connectivity correl...

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Detalles Bibliográficos
Autores principales: Joza, Stephen, Camicioli, Richard, Martin, W. R. Wayne, Wieler, Marguerite, Gee, Myrlene, Ba, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304714/
https://www.ncbi.nlm.nih.gov/pubmed/35875799
http://dx.doi.org/10.3389/fnagi.2022.874692