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Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway

Acute liver injury (ALI) is a disease that seriously threatens human health and life, and a dysregulated inflammation response is one of the main mechanisms of ALI induced by various factors. Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein with multiple biological functions....

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Detalles Bibliográficos
Autores principales: Qu, Xiao-qin, Chen, Qiong-feng, Shi, Qiao-qing, Luo, Qian-qian, Zheng, Shuang-yan, Li, Yan-hong, Bai, Liang-yu, Gan, Shuai, Zhou, Xiao-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304715/
https://www.ncbi.nlm.nih.gov/pubmed/35874667
http://dx.doi.org/10.3389/fimmu.2022.901566