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Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma
Ovarian clear cell carcinoma (OCCC) is an understudied poor prognosis subtype of ovarian cancer lacking in effective targeted therapies. Efforts to define molecular drivers of OCCC malignancy may lead to new therapeutic targets and approaches. Among potential targets are secreted proteases, enzymes...
Autores principales: | Mehner, Christine, Hockla, Alexandra, Coban, Mathew, Madden, Benjamin, Estrada, Rosendo, Radisky, Derek C., Radisky, Evette S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304776/ https://www.ncbi.nlm.nih.gov/pubmed/35716777 http://dx.doi.org/10.1016/j.jbc.2022.102146 |
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