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Mapping interactions between the CRAC activation domain and CC1 regulating the activity of the ER Ca(2+) sensor STIM1
Stromal interaction molecule 1 (STIM1) is a widely expressed protein that functions as the endoplasmic reticulum (ER) Ca(2+) sensor and activator of Orai1 channels. In resting cells with replete Ca(2+) stores, an inhibitory clamp formed by the coiled-coil 1 (CC1) domain interacting with the CRAC-act...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304783/ https://www.ncbi.nlm.nih.gov/pubmed/35724962 http://dx.doi.org/10.1016/j.jbc.2022.102157 |