Substoichiometric Hsp104 regulates the genesis and persistence of self-replicable amyloid seeds of Sup35 prion domain

Prion-like self-perpetuating conformational conversion of proteins is involved in both transmissible neurodegenerative diseases in mammals and non-Mendelian inheritance in yeast. The transmissibility of amyloid-like aggregates is dependent on the stoichiometry of chaperones such as heat shock protei...

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Detalles Bibliográficos
Autores principales: Mahapatra, Sayanta, Sarbahi, Anusha, Madhu, Priyanka, Swasthi, Hema M., Sharma, Abhishek, Singh, Priyanka, Mukhopadhyay, Samrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304785/
https://www.ncbi.nlm.nih.gov/pubmed/35714774
http://dx.doi.org/10.1016/j.jbc.2022.102143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304785/
https://www.ncbi.nlm.nih.gov/pubmed/35714774
http://dx.doi.org/10.1016/j.jbc.2022.102143

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