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Mineralocorticoid receptor-antagonism prevents COVID-19-dependent glycocalyx damage

Proinflammatory cytokines target vascular endothelial cells during COVID-19 infections. In particular, the endothelial glycocalyx (eGC), a proteoglycan-rich layer on top of endothelial cells, was identified as a vulnerable, vasoprotective structure during infections. Thus, eGC damage can be seen as...

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Detalles Bibliográficos
Autores principales: Fels, Benedikt, Acharya, Sovon, Vahldieck, Carl, Graf, Tobias, Käding, Nadja, Rupp, Jan, Kusche-Vihrog, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304794/
https://www.ncbi.nlm.nih.gov/pubmed/35867189
http://dx.doi.org/10.1007/s00424-022-02726-3