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Ascorbic acid can alleviate the degradation of levodopa and carbidopa induced by magnesium oxide

INTRODUCTION: Levodopa and carbidopa are reported to be degraded by magnesium oxide (MgO), which is often used as a laxative for patients with Parkinson's disease (PD). Ascorbic acid (AsA) can stabilize levodopa and carbidopa solutions; however, the effect of AsA on the degradation of levodopa...

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Detalles Bibliográficos
Autores principales: Miyaue, Noriyuki, Kubo, Madoka, Nagai, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304850/
https://www.ncbi.nlm.nih.gov/pubmed/35712877
http://dx.doi.org/10.1002/brb3.2672