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An Abundant and Diverse New Family of Electron Bifurcating Enzymes With a Non-canonical Catalytic Mechanism

Microorganisms utilize electron bifurcating enzymes in metabolic pathways to carry out thermodynamically unfavorable reactions. Bifurcating FeFe-hydrogenases (HydABC) reversibly oxidize NADH (E′∼−280 mV, under physiological conditions) and reduce protons to H(2) gas (E°′−414 mV) by coupling this end...

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Detalles Bibliográficos
Autores principales: Schut, Gerrit J., Haja, Dominik K., Feng, Xiang, Poole, Farris L., Li, Huilin, Adams, Michael W. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304861/
https://www.ncbi.nlm.nih.gov/pubmed/35875533
http://dx.doi.org/10.3389/fmicb.2022.946711