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CSTF2 Promotes Hepatocarcinogenesis and Hepatocellular Carcinoma Progression via Aerobic Glycolysis

BACKGROUND: The shortening of 3’ untranslated regions (3’UTRs) of messenger RNAs(mRNAs) by alternative polyadenylation (APA) is an important mechanism for oncogene activation. Cleavage stimulation factor 2 (CSTF2), an important regulator of APA, has been reported to have a tumorigenic function in ur...

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Detalles Bibliográficos
Autores principales: Chen, Zhimin, Hao, Weijie, Tang, Jingzhi, Gao, Wei-Qiang, Xu, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304882/
https://www.ncbi.nlm.nih.gov/pubmed/35875122
http://dx.doi.org/10.3389/fonc.2022.897804