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The Cholesterol-Binding Sequence in Monomeric C-Reactive Protein Binds to the SARS-CoV-2 Spike Receptor-Binding Domain and Blocks Interaction With Angiotensin-Converting Enzyme 2

The receptor-binding domain (RBD) of the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the human angiotensin-converting enzyme 2 (ACE2) receptor, which is a prerequisite for the virus to enter the cell. C-reactive protein (CRP) is an important marker of infla...

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Detalles Bibliográficos
Autores principales: Li, Hai-yun, Gao, Ning, Liu, Cheng-yang, Liu, Xiao-ling, Wu, Feng, Dai, Nini, Han, Jing, Li, Qiu-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304929/
https://www.ncbi.nlm.nih.gov/pubmed/35874670
http://dx.doi.org/10.3389/fimmu.2022.918731