Robust Colonic Epithelial Regeneration and Amelioration of Colitis via FZD-Specific Activation of Wnt Signaling

BACKGROUND AND AIMS: Current management of inflammatory bowel disease leaves a clear unmet need to treat the severe epithelial damage. Modulation of Wnt signaling might present an opportunity to achieve histological remission and mucosal healing when treating IBD. Exogenous R-spondin, which amplifie...

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Detalles Bibliográficos
Autores principales: Xie, Liqin, Fletcher, Russell B., Bhatia, Diksha, Shah, Darshini, Phipps, Jacqueline, Deshmukh, Shalaka, Zhang, Haili, Ye, Jingjing, Lee, Sungjin, Le, Lucas, Newman, Maureen, Chen, Hui, Sura, Asmiti, Gupta, Suhani, Sanman, Laura E., Yang, Fan, Meng, Weixu, Baribault, Helene, Vanhove, Geertrui F., Yeh, Wen-Chen, Li, Yang, Lu, Chenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305022/
https://www.ncbi.nlm.nih.gov/pubmed/35569814
http://dx.doi.org/10.1016/j.jcmgh.2022.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305022/
https://www.ncbi.nlm.nih.gov/pubmed/35569814
http://dx.doi.org/10.1016/j.jcmgh.2022.05.003

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