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Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis

The extravasation of leukocytes is a critical step during inflammation that requires the localized opening of the endothelial barrier. This process is initiated by the close interaction of leukocytes with various adhesion molecules such as ICAM-1 on the surface of endothelial cells. Here we reveal t...

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Detalles Bibliográficos
Autores principales: Wang, ShengPeng, Wang, Bianbian, Shi, Yue, Möller, Tanja, Stegmeyer, Rebekka I., Strilic, Boris, Li, Ting, Yuan, Zuyi, Wang, Changhe, Wettschureck, Nina, Vestweber, Dietmar, Offermanns, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305087/
https://www.ncbi.nlm.nih.gov/pubmed/35443048
http://dx.doi.org/10.1182/blood.2021014614