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Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis
The extravasation of leukocytes is a critical step during inflammation that requires the localized opening of the endothelial barrier. This process is initiated by the close interaction of leukocytes with various adhesion molecules such as ICAM-1 on the surface of endothelial cells. Here we reveal t...
Autores principales: | Wang, ShengPeng, Wang, Bianbian, Shi, Yue, Möller, Tanja, Stegmeyer, Rebekka I., Strilic, Boris, Li, Ting, Yuan, Zuyi, Wang, Changhe, Wettschureck, Nina, Vestweber, Dietmar, Offermanns, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305087/ https://www.ncbi.nlm.nih.gov/pubmed/35443048 http://dx.doi.org/10.1182/blood.2021014614 |
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