Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class

The enzymes of the 2‐C‐methylerythritol‐d‐erythritol 4‐phosphate (MEP) pathway (MEP pathway or non‐mevalonate pathway) are responsible for the synthesis of universal precursors of the large and structurally diverse family of isoprenoids. This pathway is absent in humans, but present in many pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Diamanti, Eleonora, Hamed, Mostafa M., Lacour, Antoine, Bravo, Patricia, Illarionov, Boris, Fischer, Markus, Rottmann, Matthias, Witschel, Matthias, Hirsch, Anna K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305118/
https://www.ncbi.nlm.nih.gov/pubmed/34918860
http://dx.doi.org/10.1002/cmdc.202100679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305118/
https://www.ncbi.nlm.nih.gov/pubmed/34918860
http://dx.doi.org/10.1002/cmdc.202100679

Ejemplares similares