Cargando…

Smooth muscle Rac1 contributes to pulmonary hypertension

BACKGROUND AND PURPOSE: Pulmonary hypertension (PH) is a multifactorial chronic disease characterized by an increase in pulmonary artery (PA) resistance leading to right ventricle (RV) failure. Endothelial dysfunction and alteration of NO/cGMP signalling in PA plays a major role in PH. We recently d...

Descripción completa

Detalles Bibliográficos
Autores principales: Dilasser, Florian, Rio, Marc, Rose, Lindsay, Tesse, Angela, Guignabert, Christophe, Loirand, Gervaise, Sauzeau, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305120/
https://www.ncbi.nlm.nih.gov/pubmed/35064565
http://dx.doi.org/10.1111/bph.15805