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Expanding the Repertoire of Low‐Molecular‐Weight Pentafluorosulfanyl‐Substituted Scaffolds

The pentafluorosulfanyl (‐SF(5)) functional group is of increasing interest as a bioisostere in medicinal chemistry. A library of SF(5)‐containing compounds, including amide, isoxazole, and oxindole derivatives, was synthesised using a range of solution‐based and solventless methods, including micro...

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Detalles Bibliográficos
Autores principales: Jose, Arathy, Guest, Daniel, LeGay, Remi, Tizzard, Graham J., Coles, Simon J., Derveni, Mariliza, Wright, Edward, Marrison, Lester, Lee, Alpha A., Morris, Aaron, Robinson, Matt, von Delft, Frank, Fearon, Daren, Koekemoer, Lizbé, Matviuk, Tetiana, Aimon, Anthony, Schofield, Christopher J., Malla, Tika R., London, Nir, Greenland, Barnaby W., Bagley, Mark C., Spencer, John, The Covid Moonshot Consortium
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305131/
https://www.ncbi.nlm.nih.gov/pubmed/35191598
http://dx.doi.org/10.1002/cmdc.202100641