Integrative multi‐omic analysis reveals neurodevelopmental gene dysregulation in CIC ‐knockout and IDH1 ‐mutant cells

Capicua (CIC)'s transcriptional repressor function is implicated in neurodevelopment and in oligodendroglioma (ODG) aetiology. However, CIC's role in these contexts remains obscure, primarily from our currently limited knowledge regarding its biological functions. Moreover, CIC mutations i...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Stephen D, Song, Jungeun, LeBlanc, Veronique G, Marra, Marco A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305137/
https://www.ncbi.nlm.nih.gov/pubmed/34767259
http://dx.doi.org/10.1002/path.5835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305137/
https://www.ncbi.nlm.nih.gov/pubmed/34767259
http://dx.doi.org/10.1002/path.5835

Ejemplares similares