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Kakonein restores hyperglycemia‐induced macrophage digestion dysfunction through regulation of cathepsin B‐dependent NLRP3 inflammasome activation

In hyperglycemia‐induced complications, macrophages play important roles in disease progression, and altered digestion is a key feature that dictates macrophage function. Recent evidence indicates that kakonein (Ka) possesses anti‐inflammatory activities for hyperglycemia‐induced complication. In th...

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Detalles Bibliográficos
Autores principales: Lian, Dawei, Zhu, Li, Yu, Yunhong, Zhang, Xiaojuan, Lin, Yike, Liu, Jiaying, Han, Ruifang, Guo, Yitong, Cai, Dongpeng, Xiao, Wenjing, Chen, Yulin, He, Hong, Xu, Danping, Zheng, Chaoyang, Wang, Xiao, Huang, Yi, Chen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305139/
https://www.ncbi.nlm.nih.gov/pubmed/35224772
http://dx.doi.org/10.1002/JLB.3MA0821-418R